The clinical application of Filmarray respiratory panel in children especially with severe respiratory tract infections
نویسندگان
چکیده
Abstract Background Respiratory tract infections (RTIs) are the common diseases in children and routine detection methods frequently fail to identify infectious pathogens especially for viruses. The Filmarray respiratory panel (FARP) can reliably rapidly viruses bacteria pathogens. This study is evaluate performance clinical significance of FARP children. Methods Children diagnosed with RTIs pediatric intensive care unit (PICU) were enrolled this study. Nasopharyngeal secretion (NPS) samples these collected assay 17 microbiological performed. Clinical data all patients was also evaluated. Results A total 90 into 58 (64.4%) positive 13 by FARP, 18 being detected multiple-virus (31.3%, 18/58). Human rhinovirus/enterovirus (21.0%%, 17/58) predominant pathogen, followed adenovirus (18.5%). Higher proportions various identified infant toddler (0–2 years) groups human mostly virus. Adenovirus group aged 3–5 years, but only three including M.pneumoniae , syncytial virus, found age (6–14 years). Among patients, significant differences antibiotic prescription use glucocorticoid between single-organism-positive multi-organism-positive ( P < 0.05). Furthermore, there difference anti-virus usage severe non Conclusions demonstrated that provide rapid virus atypical children, infections.
منابع مشابه
Epidemiological and clinical evaluation of children with respiratory virus infections
Background :Respiratory viruses are the leading cause of respiratory tract infections among children and are responsible for causing morbidity and mortality worldwide. This study was performed to detect viruses in children with respiratory infections and describe their epidemiology and clinical characteristics. Methods : In this descriptive cross sectional study, throat swabs and wash speci...
متن کاملEvaluation of the BioFire FilmArray respiratory panel and the GenMark eSensor respiratory viral panel on lower respiratory tract specimens.
We evaluated the performance characteristics of the FilmArray respiratory panel and the eSensor respiratory viral panel on clinical and spiked lower respiratory tract specimens (LRTS). The overall agreement between the two methods was 89.5% (51/57). The lower limit of detection of both assays for all targets in LRTS was comparable to that for nasopharyngeal swab specimens.
متن کاملFungal Infections of Respiratory Tract-Final Section
Histoplasma capsulatum var. capsulatum, Blastomyces dermatitidis, Coccidioides immitis, Paracoccidioides brasiliensis, and Penicillium marneffei are endemic dimorphic fungi that may infect the respiratory tract. Sporothrix schenkeii, which manifests the typical thermal dimorphism of the endemic dimorphic organisms, does not seem to follow a geographically defined endemic pattern of distribution...
متن کاملBocavirus in Children with Respiratory Tract Infections
6. Clarridge JE III, Raich TJ, Pirwani D, Simon B, Tsai L, Rodriguez-Barradas MC, et al. Strategy to detect and identify Bartonella species in routine clinical laboratory yields Bartonella henselae from human immunodefi ciency virus–positive patient and unique Bartonella strain from his cat. J Clin Microbiol. 1995;33:2107–13. 7. Mediannikov O, Cabre O, Qu F, Socolovschi C, Davoust B, Marié JL, ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BMC Infectious Diseases
سال: 2021
ISSN: ['1471-2334']
DOI: https://doi.org/10.1186/s12879-021-05900-7